1ME6
CRYSTAL STRUCTURE OF PLASMEPSIN II, AN ASPARTYL PROTEASE FROM PLASMODIUM FALCIPARUM, IN COMPLEX WITH A STATINE-BASED INHIBITOR
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Plasmepsin II | polymer | 329 | 36953.7 | 2 | UniProt (P46925) Pfam (PF00026) | Plasmodium falciparum (malaria parasite P. falciparum) | Aspartic hemoglobinase II, PFAPD |
| 2 | C, D (A, B) | 3-HYDROXY-6-METHYL-4-(3-METHYL-2-(3-METHYL-2-(3-METHYL-BUTYRYLAMINO)-BUTYRYLAMINO)-BUTYRYLAMINO)-HEPTANOIC ACID ETHYL ESTER | non-polymer | 485.7 | 2 | Chemie (IVS) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 73907.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 971.3 | |
| All* | Total formula weight | 74878.8 |
