1M9N

CRYSTAL STRUCTURE OF THE HOMODIMERIC BIFUNCTIONAL TRANSFORMYLASE AND CYCLOHYDROLASE ENZYME AVIAN ATIC IN COMPLEX WITH AICAR AND XMP AT 1.93 ANGSTROMS.

Summary for 1M9N

• Entry DOI: 10.2210/pdb1m9n/pdb
• Related: 1G8M
• Descriptor: AICAR TRANSFORMYLASE-IMP CYCLOHYDROLASE, POTASSIUM ION, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, ... (5 entities in total)
• Functional Keywords: homodimer, 2 functional domains; impch domain = alpha/beta/alpha; aicar tfase = 2 alpha/beta/alpha domains, 1 alpha + beta domain, transferase, hydrolase
• Biological source: Gallus gallus (chicken)
• Total number of polymer chains: 2
• Total formula weight: 134823.22

Authors

Wolan, D.W.,Greasly, S.E.,Beardsley, G.P.,Wilson, I.A. (deposition date: 2002-07-29, release date: 2003-01-07, Last modification date: 2024-02-14)

• Primary citation: Wolan, D.W.,Greasly, S.E.,Beardsley, G.P.,Wilson, I.A.; Structural Insights into the Avian AICAR Transformylase Mechanism.; Biochemistry, 41:15505-15513, 2002; PubMed: 12501179; DOI: 10.1021/bi020505x

Experimental method

X-RAY DIFFRACTION (1.93 Å)