1M2N
Sir2 homologues (D102G/F159A/R170A) mutant-2'-O-acetyl ADP ribose complex
Summary for 1M2N
Entry DOI | 10.2210/pdb1m2n/pdb |
Related | 1M2G 1M2H 1M2J 1M2K |
Descriptor | Silent Information Regulator 2, ZINC ION, 2'-O-ACETYL ADENOSINE-5-DIPHOSPHORIBOSE, ... (4 entities in total) |
Functional Keywords | protein-ligand complex, gene regulation |
Biological source | Archaeoglobus fulgidus |
Cellular location | Cytoplasm (Probable): O28597 |
Total number of polymer chains | 2 |
Total formula weight | 56195.05 |
Authors | |
Primary citation | Chang, J.H.,Kim, H.C.,Hwang, K.Y.,Lee, J.W.,Jackson, S.P.,Bell, S.D.,Cho, Y. Structural basis for the NAD-dependent deacetylase mechanism of Sir2 J.BIOL.CHEM., 277:34489-34498, 2003 Cited by PubMed: 12091395DOI: 10.1074/jbc.M205460200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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