1M1L
Human Suppressor of Fused (N-terminal domain)
Summary for 1M1L
Entry DOI | 10.2210/pdb1m1l/pdb |
Descriptor | Suppressor of Fused (2 entities in total) |
Functional Keywords | gene regulation, hedgehog signaling, signal transduction, fused, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9UMX1 |
Total number of polymer chains | 4 |
Total formula weight | 106370.92 |
Authors | Merchant, M.,Vajdos, F.F.,Ultsch, M.,Maun, H.R.,Wendt, U.,Cannon, J.,Lazarus, R.A.,de Vos, A.M.,de Sauvage, F.J. (deposition date: 2002-06-19, release date: 2004-02-03, Last modification date: 2024-02-14) |
Primary citation | Merchant, M.,Vajdos, F.F.,Ultsch, M.,Maun, H.R.,Wendt, U.,Cannon, J.,Desmarais, W.,Lazarus, R.A.,de Vos, A.M.,de Sauvage, F.J. Suppressor of fused regulates Gli activity through a dual binding mechanism Mol.Cell.Biol., 24:8627-8641, 2004 Cited by PubMed: 15367681DOI: 10.1128/MCB.24.19.8627-8641.2004 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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