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1LWW

Borohydride-trapped hOgg1 Intermediate Structure Co-Crystallized with 8-bromoguanine

Summary for 1LWW
Entry DOI10.2210/pdb1lww/pdb
Related1EBM 1FN7 1HU0 1LWV 1LWY
Descriptor5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 8-OXOGUANINE DNA GLYCOSYLASE, ... (6 entities in total)
Functional Keywordsdna repair, dna glycosylase, protein/dna, borohydride, covalent trapping, product-assisted catalysis, reaction intermediate, hydrolase-dna complex, hydrolase/dna
Biological sourceHomo sapiens (human)
Cellular locationNucleus, nucleoplasm. Isoform 1A: Nucleus. Isoform 2A: Mitochondrion: O15527
Total number of polymer chains3
Total formula weight45698.14
Authors
Fromme, J.C.,Bruner, S.D.,Yang, W.,Karplus, M.,Verdine, G.L. (deposition date: 2002-06-03, release date: 2003-02-25, Last modification date: 2011-07-13)
Primary citationFromme, J.C.,Bruner, S.D.,Yang, W.,Karplus, M.,Verdine, G.L.
Product-Assisted Catalysis in Base Excision DNA Repair
Nat.Struct.Biol., 10:204-211, 2003
Cited by
PubMed: 12592398
DOI: 10.1038/nsb902
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

217705

数据于2024-03-27公开中

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