1LUD
SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 24 STRUCTURES
Summary for 1LUD
| Entry DOI | 10.2210/pdb1lud/pdb |
| Related | 1AO8 1BZF 3DFR |
| NMR Information | BMRB: 5396 |
| Descriptor | DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM (3 entities in total) |
| Functional Keywords | dhfr, inhibitor-enzyme complex, oxidoreductase |
| Biological source | Lactobacillus casei |
| Total number of polymer chains | 1 |
| Total formula weight | 19368.34 |
| Authors | Polshakov, V.I.,Smirnov, E.G.,Birdsall, B.,Kelly, G.,Feeney, J. (deposition date: 2002-05-22, release date: 2002-12-18, Last modification date: 2024-05-01) |
| Primary citation | Polshakov, V.I.,Smirnov, E.G.,Birdsall, B.,Kelly, G.,Feeney, J. NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH J.Biomol.Nmr, 24:67-70, 2002 Cited by PubMed: 12449420DOI: 10.1023/A:1020659713373 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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