1LMW
LMW U-PA Structure complexed with EGRCMK (GLU-GLY-ARG Chloromethyl Ketone)
Summary for 1LMW
Entry DOI | 10.2210/pdb1lmw/pdb |
Related PRD ID | PRD_000288 |
Descriptor | UROKINASE-TYPE PLASMINOGEN ACTIVATOR, L-alpha-glutamyl-N-{(1S)-4-{[amino(iminio)methyl]amino}-1-[(1S)-2-chloro-1-hydroxyethyl]butyl}glycinamide (3 entities in total) |
Functional Keywords | fibrinolysis, trypsin-like serine protease, serine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P00749 P00749 |
Total number of polymer chains | 4 |
Total formula weight | 63164.99 |
Authors | Spraggon, G.S.,Phillips, C.,Nowak, U.K.,Ponting, C.P.,Saunders, D.,Dobson, C.M.,Stuart, D.I.,Jones, E.Y. (deposition date: 1995-07-26, release date: 1996-01-29, Last modification date: 2013-02-27) |
Primary citation | Spraggon, G.,Phillips, C.,Nowak, U.K.,Ponting, C.P.,Saunders, D.,Dobson, C.M.,Stuart, D.I.,Jones, E.Y. The crystal structure of the catalytic domain of human urokinase-type plasminogen activator. Structure, 3:681-691, 1995 Cited by PubMed: 8591045DOI: 10.1016/S0969-2126(01)00203-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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