1LF2
CRYSTAL STRUCTURE OF PLASMEPSIN II FROM P FALCIPARUM IN COMPLEX WITH INHIBITOR RS370
Summary for 1LF2
Entry DOI | 10.2210/pdb1lf2/pdb |
Related | 1LF3 1LF4 1LFE |
Descriptor | Plasmepsin 2, 3-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE (3 entities in total) |
Functional Keywords | plasmepsin, plasmodium falciparum, aspartic protease, hydrolase |
Biological source | Plasmodium falciparum (malaria parasite P. falciparum) |
Cellular location | Vacuole: P46925 |
Total number of polymer chains | 1 |
Total formula weight | 37611.51 |
Authors | Asojo, O.A.,Afonina, E.,Gulnik, S.V.,Yu, B.,Erickson, J.W.,Randad, R.,Mehadjed, D.,Silva, A.M. (deposition date: 2002-04-10, release date: 2002-10-10, Last modification date: 2021-10-27) |
Primary citation | Asojo, O.A.,Afonina, E.,Gulnik, S.V.,Yu, B.,Erickson, J.W.,Randad, R.,Medjahed, D.,Silva, A.M. Structures of Ser205 mutant plasmepsin II from Plasmodium falciparum at 1.8 A in complex with the inhibitors rs367 and rs370. Acta Crystallogr.,Sect.D, 58:2001-2008, 2002 Cited by PubMed: 12454457DOI: 10.1107/S0907444902014695 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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