1LF2
CRYSTAL STRUCTURE OF PLASMEPSIN II FROM P FALCIPARUM IN COMPLEX WITH INHIBITOR RS370
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Plasmepsin 2 | polymer | 331 | 37079.8 | 1 | UniProt (P46925) Pfam (PF00026) In PDB | Plasmodium falciparum (malaria parasite P. falciparum) | Aspartic hemoglobinase II, PFAPD |
| 2 | A | 3-AMINO-N-{4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-1-ISOBUTYL-5-PHENYL-PENTYL}-BENZAMIDE | non-polymer | 531.7 | 1 | Chemie (R37) | |||
| 3 | water | water | 18.0 | 338 | Chemie (HOH) |
Sequence modifications
A: -1 - 329 (UniProt: P46925)
| PDB | External Database | Details |
|---|---|---|
| Ser 205 | Met 329 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37079.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 531.7 | |
| All* | Total formula weight | 37611.5 |
