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1KZY

Crystal Structure of the 53bp1 BRCT Region Complexed to Tumor Suppressor P53

Summary for 1KZY
Entry DOI10.2210/pdb1kzy/pdb
DescriptorCELLULAR TUMOR ANTIGEN P53, TUMOR SUPPRESSOR P53-BINDING PROTEIN 1, ZINC ION, ... (4 entities in total)
Functional Keywordstandem-brct and linker complexed with non-brct protein, three-helix bundle, parallel beta sheet, dna binding protein, protein binding
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm. Isoform 1: Nucleus. Isoform 2: Nucleus. Isoform 3: Nucleus. Isoform 4: Nucleus. Isoform 7: Nucleus. Isoform 8: Nucleus. Isoform 9: Cytoplasm: P04637
Nucleus: Q12888
Total number of polymer chains4
Total formula weight102558.84
Authors
Joo, W.S.,Jeffrey, P.D.,Cantor, S.B.,Finnin, M.S.,Livingston, D.M.,Pavletich, N.P. (deposition date: 2002-02-08, release date: 2002-03-20, Last modification date: 2011-07-13)
Primary citationJoo, W.S.,Jeffrey, P.D.,Cantor, S.B.,Finnin, M.S.,Livingston, D.M.,Pavletich, N.P.
Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure.
Genes Dev., 16:583-593, 2002
Cited by
PubMed: 11877378
DOI: 10.1101/gad.959202
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.5 Å)
Structure validation

217705

건을2024-03-27부터공개중

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