1KWR

HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH INHIBITOR 0134-36

Summary for 1KWR

Entry DOI	10.2210/pdb1kwr/pdb
Related	1KWQ
Descriptor	Carbonic anhydrase II, ZINC ION, 1-METHYL-3-OXO-1,3-DIHYDRO-BENZO[C]ISOTHIAZOLE-5-SULFONIC ACID AMIDE, ... (4 entities in total)
Functional Keywords	lyase, zinc, inhibitor
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm : P00918
Total number of polymer chains	1
Total formula weight	29598.76
Authors	Grueneberg, S.,Stubbs, M.T. (deposition date: 2002-01-30, release date: 2003-01-07, Last modification date: 2024-02-14)
Primary citation	Gruneberg, S.,Stubbs, M.T.,Klebe, G. Successful virtual screening for novel inhibitors of human carbonic anhydrase: strategy and experimental confirmation. J.Med.Chem., 45:3588-3602, 2002 Cited by PubMed: 12166932 DOI: 10.1021/jm011112j PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation