1KJY

Crystal Structure of Human G[alpha]i1 Bound to the GoLoco Motif of RGS14

1KJY の概要

• エントリーDOI: 10.2210/pdb1kjy/pdb
• 分子名称: GUANINE NUCLEOTIDE-BINDING PROTEIN G(I), ALPHA-1 SUBUNIT, REGULATOR OF G-PROTEIN SIGNALING 14, CESIUM ION, ... (6 entities in total)
• 機能のキーワード: protein-peptide complex, signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus (By similarity): P63096; Nucleus: O08773
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 85434.52

構造登録者

Kimple, R.J.,Kimple, M.E.,Betts, L.,Sondek, J.,Siderovski, D.P. (登録日: 2001-12-05, 公開日: 2002-05-08, 最終更新日: 2023-08-16)

• 主引用文献: Kimple, R.J.,Kimple, M.E.,Betts, L.,Sondek, J.,Siderovski, D.P.; Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits.; Nature, 416:878-881, 2002; PubMed: 11976690; DOI: 10.1038/416878a

実験手法

X-RAY DIFFRACTION (2.7 Å)