1KJ7

SUBSTRATE SHAPE DETERMINES SPECIFICITY OF RECOGNITION RECOGNITION FOR HIV-1 PROTEASE: ANALYSIS OF CRYSTAL STRUCTURES OF SIX SUBSTRATE COMPLEXES

Summary for 1KJ7

Entry DOI	10.2210/pdb1kj7/pdb
Related	1F7A 1KJ4 1KJF 1KJG 1KJH
Descriptor	POL POLYPROTEIN, gag polyprotein, ACETATE ION, ... (4 entities in total)
Functional Keywords	p2-nucleocapsid, substrate recognition, hydrolase
Biological source	Human immunodeficiency virus 1
Cellular location	Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03369 P20875
Total number of polymer chains	3
Total formula weight	23016.11
Authors	Schiffer, C.A. (deposition date: 2001-12-04, release date: 2002-03-06, Last modification date: 2023-08-16)
Primary citation	Prabu-Jeyabalan, M.,Nalivaika, E.,Schiffer, C.A. Substrate shape determines specificity of recognition for HIV-1 protease: analysis of crystal structures of six substrate complexes. Structure, 10:369-381, 2002 Cited by PubMed: 12005435 DOI: 10.1016/S0969-2126(02)00720-7 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation