1KJH

SUBSTRATE SHAPE DETERMINES SPECIFICITY OF RECOGNITION RECOGNITION FOR HIV-1 PROTEASE: ANALYSIS OF CRYSTAL STRUCTURES OF SIX SUBSTRATE COMPLEXES

Summary for 1KJH

• Entry DOI: 10.2210/pdb1kjh/pdb
• Related: 1F7A 1KJ4 1KJ7 1KJF 1KJG
• Descriptor: POL POLYPROTEIN, ACETATE ION, ... (4 entities in total)
• Functional Keywords: rnase h, integrase, substrate recognition, hydrolase
• Biological source: Human immunodeficiency virus 1
• Cellular location: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03369
• Total number of polymer chains: 3
• Total formula weight: 22909.13

Authors

Schiffer, C.A. (deposition date: 2001-12-04, release date: 2002-03-06, Last modification date: 2023-08-16)

• Primary citation: Prabu-Jeyabalan, M.,Nalivaika, E.,Schiffer, C.A.; Substrate shape determines specificity of recognition for HIV-1 protease: analysis of crystal structures of six substrate complexes.; Structure, 10:369-381, 2002; PubMed: 12005435; DOI: 10.1016/S0969-2126(02)00720-7

Experimental method

X-RAY DIFFRACTION (2 Å)