1KIM
CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE I COMPLEXED WITH DEOXYTHYMIDINE
Replaces: 1KINSummary for 1KIM
Entry DOI | 10.2210/pdb1kim/pdb |
Descriptor | THYMIDINE KINASE, SULFATE ION, THYMIDINE, ... (4 entities in total) |
Functional Keywords | transferase, phosphotransferase, thymidine kinase, viridae, ds-dna enveloped viruses, herpesviridae, alphaherpesvirinae |
Biological source | Herpes simplex virus (type 1 / strain 17) |
Total number of polymer chains | 2 |
Total formula weight | 80401.72 |
Authors | Champness, J.N.,Bennett, M.S.,Wien, F.,Brown, D.G.,Visse, R.,Sandhu, G.,Davies, A.,Rizkallah, P.J.,Melitz, C.,Summers, W.C.,Sanderson, M.R. (deposition date: 1997-11-12, release date: 1998-05-20, Last modification date: 2024-02-14) |
Primary citation | Champness, J.N.,Bennett, M.S.,Wien, F.,Visse, R.,Summers, W.C.,Herdewijn, P.,de Clerq, E.,Ostrowski, T.,Jarvest, R.L.,Sanderson, M.R. Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands. Proteins, 32:350-361, 1998 Cited by PubMed: 9715911DOI: 10.1002/(SICI)1097-0134(19980815)32:3<350::AID-PROT10>3.0.CO;2-8 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.14 Å) |
Structure validation
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