Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004797 | molecular_function | thymidine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006230 | biological_process | TMP biosynthetic process |
| A | 0009157 | biological_process | deoxyribonucleoside monophosphate biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0071897 | biological_process | DNA biosynthetic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004797 | molecular_function | thymidine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006230 | biological_process | TMP biosynthetic process |
| B | 0009157 | biological_process | deoxyribonucleoside monophosphate biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0071897 | biological_process | DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 3 |
| Chain | Residue |
| A | HIS58 |
| A | GLY59 |
| A | MET60 |
| A | GLY61 |
| A | LYS62 |
| A | THR63 |
| A | ARG222 |
| A | HOH409 |
| A | HOH442 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 4 |
| Chain | Residue |
| B | HIS58 |
| B | GLY59 |
| B | MET60 |
| B | GLY61 |
| B | LYS62 |
| B | THR63 |
| B | ARG222 |
| B | HOH410 |
| B | HOH441 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE THM A 1 |
| Chain | Residue |
| A | HIS58 |
| A | GLU83 |
| A | ILE97 |
| A | ILE100 |
| A | TYR101 |
| A | GLN125 |
| A | ARG163 |
| A | ALA168 |
| A | TYR172 |
| A | ARG222 |
| A | GLU225 |
| A | HOH408 |
| A | HOH409 |
| A | HOH410 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE THM B 2 |
| Chain | Residue |
| B | HIS58 |
| B | GLU83 |
| B | TYR101 |
| B | GLN125 |
| B | MET128 |
| B | ALA168 |
| B | TYR172 |
| B | GLU225 |
| B | HOH409 |
| B | HOH410 |
| B | HOH411 |
| B | HOH484 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_04029","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04029","evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 6 |
| Details | a catalytic site defined by CSA, PubMed 11262392, 9715911, 9336833 |
| Chain | Residue | Details |
| A | GLU83 | |
| A | ARG222 | |
| A | ARG220 | |
| A | ARG163 | |
| A | LYS62 | |
| A | GLU225 | |
