1KHR

Crystal Structure of Vat(D) in Complex with Virginiamycin and Coenzyme A

Summary for 1KHR

Entry DOI	10.2210/pdb1khr/pdb
Descriptor	STREPTOGRAMIN A ACETYLTRANSFERASE, VIRGINIAMYCIN M1, COENZYME A, ... (4 entities in total)
Functional Keywords	antibiotic resistance, acyltransferase, transferase-antibiotic complex, transferase/antibiotic
Biological source	Enterococcus faecium
Total number of polymer chains	6
Total formula weight	148233.94
Authors	Sugantino, M.,Roderick, S.L. (deposition date: 2001-11-30, release date: 2002-02-20, Last modification date: 2024-03-13)
Primary citation	Sugantino, M.,Roderick, S.L. Crystal structure of Vat(D): an acetyltransferase that inactivates streptogramin group A antibiotics. Biochemistry, 41:2209-2216, 2002 Cited by PubMed: 11841212 DOI: 10.1021/bi011991b PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation