1K3B

Crystal Structure of Human Dipeptidyl Peptidase I (Cathepsin C): Exclusion Domain Added to an Endopeptidase Framework Creates the Machine for Activation of Granular Serine Proteases

1K3B の概要

• エントリーDOI: 10.2210/pdb1k3b/pdb
• 分子名称: dipeptydil-peptidase I exclusion domain, dipeptydil-peptidase I light chain, dipeptydil-peptidase I heavy chain, ... (7 entities in total)
• 機能のキーワード: hydrolase
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 40120.33

構造登録者

Turk, D.,Janjic, V.,Stern, I.,Podobnik, M.,Lamba, D.,Dahl, S.W.,Lauritzen, C.,Pedersen, J.,Turk, V.,Turk, B. (登録日: 2001-10-02, 公開日: 2002-04-02, 最終更新日: 2020-07-29)

• 主引用文献: Turk, D.,Janjic, V.,Stern, I.,Podobnik, M.,Lamba, D.,Dahl, S.W.,Lauritzen, C.,Pedersen, J.,Turk, V.,Turk, B.; Structure of human dipeptidyl peptidase I (cathepsin C): exclusion domain added to an endopeptidase framework creates the machine for activation of granular serine proteases.; EMBO J., 20:6570-6582, 2001; PubMed: 11726493; DOI: 10.1093/emboj/20.23.6570

実験手法

X-RAY DIFFRACTION (2.15 Å)