1JWK

Murine Inducible Nitric Oxide Synthase Oxygenase Dimer (Delta 65) with W457A Mutation at Tetrahydrobiopterin Binding Site

1JWK の概要

• エントリーDOI: 10.2210/pdb1jwk/pdb
• 関連するPDBエントリー: 1JWJ
• 分子名称: Nitric Oxide Synthase, Inducible, octyl beta-D-glucopyranoside, PROTOPORPHYRIN IX CONTAINING FE, ... (7 entities in total)
• 機能のキーワード: nitric oxide l-arginine monooxygenase, heme, dimer, nos, tetrahydrobiopterin, oxidoreductase
• 由来する生物種: Mus musculus (house mouse)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 102730.33

構造登録者

Aoyagi, M.,Arvai, A.S.,Ghosh, S.,Stuehr, D.J.,Tainer, J.A.,Getzoff, E.D. (登録日: 2001-09-04, 公開日: 2001-10-31, 最終更新日: 2023-08-16)

• 主引用文献: Aoyagi, M.,Arvai, A.S.,Ghosh, S.,Stuehr, D.J.,Tainer, J.A.,Getzoff, E.D.; Structures of tetrahydrobiopterin binding-site mutants of inducible nitric oxide synthase oxygenase dimer and implicated roles of Trp457.; Biochemistry, 40:12826-12832, 2001; PubMed: 11669619; DOI: 10.1021/bi011183k

実験手法

X-RAY DIFFRACTION (2.3 Å)