1JWK
Murine Inducible Nitric Oxide Synthase Oxygenase Dimer (Delta 65) with W457A Mutation at Tetrahydrobiopterin Binding Site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nitric Oxide Synthase, Inducible | polymer | 434 | 50109.0 | 2 | UniProt (P29477) Pfam (PF02898) | Mus musculus (house mouse) | NOS, type II, Inducible NOS, INOS, Macrophage NOS, MAC-NOS |
| 2 | C, H (A, B) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 2 | Chemie (BOG) | |||
| 3 | D, I (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 4 | E, J (A, B) | 7,8-DIHYDROBIOPTERIN | non-polymer | 239.2 | 2 | Chemie (HBI) | |||
| 5 | F, K (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 6 | G (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | L, M (A, B) | water | water | 18.0 | 461 | Chemie (HOH) |
Sequence modifications
A, B: 66 - 498 (UniProt: P29477)
| PDB | External Database | Details |
|---|---|---|
| Ala 457 | Trp 457 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 100217.9 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 2512.4 | |
| All* | Total formula weight | 102730.3 |
