1JVS
Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase; a target enzyme for antimalarial drugs
Summary for 1JVS
Entry DOI | 10.2210/pdb1jvs/pdb |
Descriptor | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, SULFATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total) |
Functional Keywords | reductoisomerase, nadph, oxidoreductase |
Biological source | Escherichia coli |
Total number of polymer chains | 2 |
Total formula weight | 90402.95 |
Authors | Yajima, S.,Nonaka, T.,Kuzuyama, T.,Seto, H.,Ohsawa, K. (deposition date: 2001-08-31, release date: 2002-10-09, Last modification date: 2019-11-06) |
Primary citation | Yajima, S.,Nonaka, T.,Kuzuyama, T.,Seto, H.,Ohsawa, K. Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase complexed with cofactors: implications of a flexible loop movement upon substrate binding. J.Biochem., 131:313-317, 2002 Cited by PubMed: 11872159DOI: 10.1093/oxfordjournals.jbchem.a003105 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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