1JVS
Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase; a target enzyme for antimalarial drugs
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | polymer | 400 | 44360.0 | 2 | UniProt (P45568) Pfam (PF02670) Pfam (PF08436) Pfam (PF13288) In PDB | Escherichia coli | |
2 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
3 | A, B | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
4 | water | water | 18.0 | 278 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 397 (UniProt: P45568)
PDB | External Database | Details |
---|---|---|
Gly 0 | - | cloning artifact |
Mse 41 | Met 42 | modified residue |
Mse 55 | Met 56 | modified residue |
Mse 67 | Met 68 | modified residue |
Mse 87 | Met 88 | modified residue |
Mse 97 | Met 98 | modified residue |
Mse 135 | Met 136 | modified residue |
Mse 200 | Met 201 | modified residue |
Mse 213 | Met 214 | modified residue |
Mse 224 | Met 225 | modified residue |
Mse 225 | Met 226 | modified residue |
Mse 245 | Met 246 | modified residue |
Mse 258 | Met 259 | modified residue |
Mse 275 | Met 276 | modified residue |
Mse 283 | Met 284 | modified residue |
Mse 321 | Met 322 | modified residue |
Mse 366 | Met 367 | modified residue |
Mse 368 | Met 369 | modified residue |
Mse 393 | Met 394 | modified residue |
Ser 398 | - | cloning artifact |
Ala 399 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 88720.0 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1683.0 | |
All* | Total formula weight | 90403.0 |