1JT7

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L44F/L73V/V109L)

1JT7 の概要

• エントリーDOI: 10.2210/pdb1jt7/pdb
• 関連するPDBエントリー: 1JQZ
• 分子名称: acidic fibroblast growth factor, SULFATE ION, FORMIC ACID, ... (4 entities in total)
• 機能のキーワード: beta-trefoil, hormone-growth factor complex, hormone/growth factor
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted: P05230
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 67359.36

構造登録者

Brych, S.R.,Blaber, S.I.,Logan, T.M.,Blaber, M. (登録日: 2001-08-20, 公開日: 2001-12-19, 最終更新日: 2023-08-16)

• 主引用文献: Brych, S.R.,Blaber, S.I.,Logan, T.M.,Blaber, M.; Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.; Protein Sci., 10:2587-2599, 2001; PubMed: 11714927; DOI: 10.1110/ps.ps.34701

実験手法

X-RAY DIFFRACTION (1.7 Å)