1JOU

Crystal Structure of Native S195A Thrombin with an Unoccupied Active Site

Summary for 1JOU

• Entry DOI: 10.2210/pdb1jou/pdb
• Descriptor: Thrombin, light chain, Thrombin, heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: protease, proteinase, thrombin, factor iia, enzyme, blood clotting
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 107396.20

Authors

Huntington, J.A.,Esmon, C.T. (deposition date: 2001-07-31, release date: 2001-08-10, Last modification date: 2023-08-16)

• Primary citation: Huntington, J.A.,Esmon, C.T.; The molecular basis of thrombin allostery revealed by a 1.8A structure of the slow form; Structure, 11:469-479, 2003; PubMed: 12679024; DOI: 10.1016/S0969-2126(03)00049-2

Experimental method

X-RAY DIFFRACTION (1.8 Å)