1J1J

Crystal Structure of human Translin

Summary for 1J1J

Entry DOI	10.2210/pdb1j1j/pdb
Related	1KEY
Descriptor	Translin (2 entities in total)
Functional Keywords	testis/brain rna binding protein, ssdna binding protein, rna binding protein, dna binding protein
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q15631
Total number of polymer chains	4
Total formula weight	110501.99
Authors	Sugiura, I.,Sasaki, C.,Hasegawa, T.,Kohno, T.,Sugio, S.,Moriyama, H.,Kasai, M.,Matsuzaki, T. (deposition date: 2002-12-06, release date: 2003-12-06, Last modification date: 2023-12-27)
Primary citation	Sugiura, I.,Sasaki, C.,Hasegawa, T.,Kohno, T.,Sugio, S.,Moriyama, H.,Kasai, M.,Matsuzaki, T. Structure of human translin at 2.2 A resolution. Acta Crystallogr.,Sect.D, 60:674-679, 2004 Cited by PubMed Abstract: The structure of human translin at 2.2 A resolution is reported in space group C222(1). Translin forms a tetramer in the asymmetric unit. Although the monomer structure is almost the same as the crystal structure of murine translin in space group P2(1)2(1)2, the relative positions of the tetramers differ between the human and murine translins. This suggests that the multimerization of translin is flexible; the flexibility may be related to the binding to DNA/RNA. PubMed: 15039555 DOI: 10.1107/S0907444904002549 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation