1IVH

STRUCTURE OF HUMAN ISOVALERYL-COA DEHYDROGENASE AT 2.6 ANGSTROMS RESOLUTION: STRUCTURAL BASIS FOR SUBSTRATE SPECIFICITY

Summary for 1IVH

Entry DOI	10.2210/pdb1ivh/pdb
Descriptor	ISOVALERYL-COA DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE, COENZYME A PERSULFIDE, ... (4 entities in total)
Functional Keywords	oxidoreductase, acyl-coa dehydrogenase, flavoprotein, isovaleryl-coa, isovaleric acidemia
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion matrix: P26440
Total number of polymer chains	4
Total formula weight	178822.50
Authors	Tiffany, K.A.,Roberts, D.L.,Wang, M.,Paschke, R.,Mohsen, A.-W.A.,Vockley, J.,Kim, J.J.P. (deposition date: 1997-05-15, release date: 1998-05-20, Last modification date: 2024-04-03)
Primary citation	Tiffany, K.A.,Roberts, D.L.,Wang, M.,Paschke, R.,Mohsen, A.W.,Vockley, J.,Kim, J.J. Structure of human isovaleryl-CoA dehydrogenase at 2.6 A resolution: structural basis for substrate specificity,. Biochemistry, 36:8455-8464, 1997 Cited by PubMed: 9214289 DOI: 10.1021/bi970422u PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation