1IS8

Crystal structure of rat GTPCHI/GFRP stimulatory complex plus Zn

Summary for 1IS8

• Entry DOI: 10.2210/pdb1is8/pdb
• Related: 1IS7
• Descriptor: GTP Cyclohydrolase I, GTP Cyclohydrolase I Feedback Regulatory Protein, ZINC ION, ... (6 entities in total)
• Functional Keywords: enzyme-regulatory protein complex, hydrolase-protein binding complex, hydrolase/protein binding
• Biological source: Rattus norvegicus (Norway rat); More
• Cellular location: Cytoplasm (By similarity): P22288; Nucleus (By similarity): P70552
• Total number of polymer chains: 20
• Total formula weight: 357725.93

Authors

Maita, N.,Okada, K.,Hatakeyama, K.,Hakoshima, T. (deposition date: 2001-11-18, release date: 2002-02-20, Last modification date: 2023-12-27)

• Primary citation: Maita, N.,Okada, K.,Hatakeyama, K.,Hakoshima, T.; Crystal structure of the stimulatory complex of GTP cyclohydrolase I and its feedback regulatory protein GFRP.; Proc.Natl.Acad.Sci.USA, 99:1212-1217, 2002; PubMed: 11818540; DOI: 10.1073/pnas.022646999

Experimental method

X-RAY DIFFRACTION (2.7 Å)