1IO4
CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN-CBFBETA CORE DOMAIN HETERODIMER AND C/EBPBETA BZIP HOMODIMER BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER
Summary for 1IO4
Entry DOI | 10.2210/pdb1io4/pdb |
Related | 1CL3 1CMO 1CO1 1E50 1HJB 1HJC 2JHB |
Descriptor | CSF-1R PROMOTER, CAAT/ENHANCER BINDING PROTEIN BETA, RUNT-RELATED TRANSCRIPTION FACTOR 1, ... (7 entities in total) |
Functional Keywords | protein-dna complex, transcription factor, bzip, runx, runt, c/ebp, cbf, core binding factor, aml1, aml, transcription-dna complex, transcription/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P17676 Q03347 Nucleus (Potential): Q08024 |
Total number of polymer chains | 6 |
Total formula weight | 65658.31 |
Authors | Tahirov, T.H.,Ogata, K. (deposition date: 2001-01-10, release date: 2001-03-12, Last modification date: 2023-12-27) |
Primary citation | Tahirov, T.H.,Inoue-Bungo, T.,Morii, H.,Fujikawa, A.,Sasaki, M.,Kimura, K.,Shiina, M.,Sato, K.,Kumasaka, T.,Yamamoto, M.,Ishii, S.,Ogata, K. Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta. Cell(Cambridge,Mass.), 104:755-767, 2001 Cited by PubMed: 11257229DOI: 10.1016/S0092-8674(01)00271-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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