1ILK

INTERLEUKIN-10 CRYSTAL STRUCTURE REVEALS THE FUNCTIONAL DIMER WITH AN UNEXPECTED TOPOLOGICAL SIMILARITY TO INTERFERON GAMMA

Summary for 1ILK

Entry DOI	10.2210/pdb1ilk/pdb
Descriptor	INTERLEUKIN-10 (2 entities in total)
Functional Keywords	cytokine
Biological source	Homo sapiens (human)
Cellular location	Secreted: P22301
Total number of polymer chains	1
Total formula weight	17800.60
Authors	Zdanov, A.,Schalk-Hihi, C.,Gustchina, A.,Wlodawer, A. (deposition date: 1995-04-21, release date: 1995-07-10, Last modification date: 2024-06-05)
Primary citation	Zdanov, A.,Schalk-Hihi, C.,Gustchina, A.,Tsang, M.,Weatherbee, J.,Wlodawer, A. Crystal structure of interleukin-10 reveals the functional dimer with an unexpected topological similarity to interferon gamma. Structure, 3:591-601, 1995 Cited by PubMed: 8590020 DOI: 10.1016/S0969-2126(01)00193-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation