1ICW
INTERLEUKIN-8, MUTANT WITH GLU 38 REPLACED BY CYS AND CYS 50 REPLACED BY ALA
Summary for 1ICW
Entry DOI | 10.2210/pdb1icw/pdb |
Descriptor | INTERLEUKIN-8 (2 entities in total) |
Functional Keywords | cytokine, chemokine |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P10145 |
Total number of polymer chains | 2 |
Total formula weight | 16687.54 |
Authors | Eigenbrot, C.,Lowman, H.B.,Chee, L.,Artis, D.R. (deposition date: 1996-09-18, release date: 1997-03-12, Last modification date: 2021-11-03) |
Primary citation | Eigenbrot, C.,Lowman, H.B.,Chee, L.,Artis, D.R. Structural change and receptor binding in a chemokine mutant with a rearranged disulfide: X-ray structure of E38C/C50AIL-8 at 2 A resolution. Proteins, 27:556-566, 1997 Cited by PubMed: 9141135DOI: 10.1002/(SICI)1097-0134(199704)27:4<556::AID-PROT8>3.3.CO;2-S PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.01 Å) |
Structure validation
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