Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1ICW

INTERLEUKIN-8, MUTANT WITH GLU 38 REPLACED BY CYS AND CYS 50 REPLACED BY ALA

Summary for 1ICW
Entry DOI10.2210/pdb1icw/pdb
DescriptorINTERLEUKIN-8 (2 entities in total)
Functional Keywordscytokine, chemokine
Biological sourceHomo sapiens (human)
Cellular locationSecreted: P10145
Total number of polymer chains2
Total formula weight16687.54
Authors
Eigenbrot, C.,Lowman, H.B.,Chee, L.,Artis, D.R. (deposition date: 1996-09-18, release date: 1997-03-12, Last modification date: 2021-11-03)
Primary citationEigenbrot, C.,Lowman, H.B.,Chee, L.,Artis, D.R.
Structural change and receptor binding in a chemokine mutant with a rearranged disulfide: X-ray structure of E38C/C50AIL-8 at 2 A resolution.
Proteins, 27:556-566, 1997
Cited by
PubMed: 9141135
DOI: 10.1002/(SICI)1097-0134(199704)27:4<556::AID-PROT8>3.3.CO;2-S
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.01 Å)
Structure validation

218853

PDB entries from 2024-04-24

PDB statisticsPDBj update infoContact PDBjnumon