1I57
CRYSTAL STRUCTURE OF APO HUMAN PTP1B (C215S) MUTANT
Summary for 1I57
Entry DOI | 10.2210/pdb1i57/pdb |
Descriptor | PHOSPHO-TYROSINE PHOSPHATASE 1B, MAGNESIUM ION, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | substrate-trapping mutant, conformational change, wpd loop, phosphate-binding loop, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side : P18031 |
Total number of polymer chains | 1 |
Total formula weight | 36423.68 |
Authors | Scapin, G.,Patel, S.,Patel, V.,Kennedy, B.,Asante-Appiah, E. (deposition date: 2001-02-26, release date: 2001-08-08, Last modification date: 2023-08-09) |
Primary citation | Scapin, G.,Patel, S.,Patel, V.,Kennedy, B.,Asante-Appiah, E. The structure of apo protein-tyrosine phosphatase 1B C215S mutant: more than just an S --> O change. Protein Sci., 10:1596-1605, 2001 Cited by PubMed: 11468356DOI: 10.1110/ps.11001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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