1I57
CRYSTAL STRUCTURE OF APO HUMAN PTP1B (C215S) MUTANT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PHOSPHO-TYROSINE PHOSPHATASE 1B | polymer | 310 | 36222.1 | 1 | UniProt (P18031) Pfam (PF00102) | Homo sapiens (human) | PTP-1B, PROTEIN-TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1, PROTEIN-TYROSINE PHOSPHATASE 1B |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C, D, E, F, G (A) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 4 | H (A) | water | water | 18.0 | 250 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P18031)
| PDB | External Database | Details |
|---|---|---|
| Met -11 | - | SEE REMARK 999 |
| Asp -10 | - | SEE REMARK 999 |
| Tyr -9 | - | SEE REMARK 999 |
| Lys -8 | - | SEE REMARK 999 |
| Asp -7 | - | SEE REMARK 999 |
| Asp -6 | - | SEE REMARK 999 |
| Asp -5 | - | SEE REMARK 999 |
| Asp -4 | - | SEE REMARK 999 |
| Lys -3 | - | SEE REMARK 999 |
| Leu -2 | - | SEE REMARK 999 |
| Glu -1 | - | SEE REMARK 999 |
| Phe 0 | - | SEE REMARK 999 |
| Ser 215 | Cys 215 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36222.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 201.6 | |
| All* | Total formula weight | 36423.7 |
