1I57
CRYSTAL STRUCTURE OF APO HUMAN PTP1B (C215S) MUTANT
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | PHOSPHO-TYROSINE PHOSPHATASE 1B | polymer | 310 | 36222.1 | 1 | UniProt (P18031) Pfam (PF00102) In PDB | Homo sapiens (human) | PTP-1B, PROTEIN-TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1, PROTEIN-TYROSINE PHOSPHATASE 1B |
2 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
3 | A | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
4 | water | water | 18.0 | 250 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P18031)
PDB | External Database | Details |
---|---|---|
Met -11 | - | SEE REMARK 999 |
Asp -10 | - | SEE REMARK 999 |
Tyr -9 | - | SEE REMARK 999 |
Lys -8 | - | SEE REMARK 999 |
Asp -7 | - | SEE REMARK 999 |
Asp -6 | - | SEE REMARK 999 |
Asp -5 | - | SEE REMARK 999 |
Asp -4 | - | SEE REMARK 999 |
Lys -3 | - | SEE REMARK 999 |
Leu -2 | - | SEE REMARK 999 |
Glu -1 | - | SEE REMARK 999 |
Phe 0 | - | SEE REMARK 999 |
Ser 215 | Cys 215 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 36222.1 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 201.6 | |
All* | Total formula weight | 36423.7 |