1I13

ANALYSIS OF AN INVARIANT ASPARTIC ACID IN HPRTS-ALANINE MUTANT

1I13 の概要

• エントリーDOI: 10.2210/pdb1i13/pdb
• 関連するPDBエントリー: 1I0I 1I0L 1I14 1tc1 1tc2
• 分子名称: HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, MAGNESIUM ION, 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE, ... (6 entities in total)
• 機能のキーワード: phosphoribosyltransferase, nucleotide metabolism, purine salvage, ternary complex, catalytic base, transferase
• 由来する生物種: Trypanosoma cruzi
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 52156.24

構造登録者

Canyuk, B.,Focia, P.J.,Eakin, A.E. (登録日: 2001-01-30, 公開日: 2002-05-29, 最終更新日: 2023-08-09)

• 主引用文献: Canyuk, B.,Focia, P.J.,Eakin, A.E.; The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography.; Biochemistry, 40:2754-2765, 2001; PubMed: 11258886; DOI: 10.1021/bi001195q

実験手法

X-RAY DIFFRACTION (1.84 Å)