1HVU
HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE COMPLEXED WITH A 33-BASE NUCLEOTIDE RNA PSEUDOKNOT
Summary for 1HVU
Entry DOI | 10.2210/pdb1hvu/pdb |
Descriptor | RNA (33 NUCLEOTIDE RNA PSEUDOKNOT), PROTEIN (HIV-1 REVERSE TRANSCRIPTASE) (3 entities in total) |
Functional Keywords | complex (nucleotidyltransferase-rna), hydrolase, aspartyl protease, endonuclease, transferase-rna complex, transferase/rna |
Biological source | Human immunodeficiency virus 1 More |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P03366 P03366 |
Total number of polymer chains | 12 |
Total formula weight | 492023.45 |
Authors | Jaeger, J.,Restle, T.,Steitz, T.A. (deposition date: 1998-06-30, release date: 1999-01-13, Last modification date: 2023-08-02) |
Primary citation | Jaeger, J.,Restle, T.,Steitz, T.A. The structure of HIV-1 reverse transcriptase complexed with an RNA pseudoknot inhibitor. EMBO J., 17:4535-4542, 1998 Cited by PubMed: 9687519DOI: 10.1093/emboj/17.15.4535 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.75 Å) |
Structure validation
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