1HUT

THE STRUCTURE OF ALPHA-THROMBIN INHIBITED BY A 15-MER SINGLE-STRANDED DNA APTAMER

Summary for 1HUT
Related PRD IDPRD_000021
DescriptorDNA 5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3', ALPHA-Thrombin light chain, ALPHA-Thrombin heavy chain, ... (5 entities in total)
Functional Keywordsthrombin, blood clotting, hydrolase-hydrolase inhibitor-dna complex, hydrolase/hydrolase inhibitor/dna
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted, extracellular space: P00734 P00734
Total number of polymer chains3
Total formula weight39070.77
Authors
Padmanabhan, K.,Padmanabhan, K.P.,Ferrara, J.D.,Sadler, J.E.,Tulinsky, A. (deposition date: 1993-05-27, release date: 1994-06-22, Last modification date: 2013-02-27)
Primary citationFerrara, J.D.,Padmanabhan, K.,Padmanabhan, K.P.,Sadler, J.E.,Tulinsky, A.
The structure of alpha-thrombin inhibited by a 15-mer single-stranded DNA aptamer.
J.Biol.Chem., 268:17651-17654, 1993
PubMed: 8102368
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.9 Å)
Structure validation
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178938

PDB entries from 2021-06-16