1HUT
THE STRUCTURE OF ALPHA-THROMBIN INHIBITED BY A 15-MER SINGLE-STRANDED DNA APTAMER
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (D) | DNA 5'-D(*GP*GP*TP*TP*GP*GP*TP*GP*TP*GP*GP*TP*TP*GP*G)-3' | polymer | 15 | 4743.1 | 1 | |||
2 | B (L) | ALPHA-Thrombin light chain | polymer | 36 | 4096.5 | 1 | UniProt (P00734) Pfam (PF09396) | Homo sapiens (human) | COAGULATION FACTOR II, THROMBIN |
3 | C (H) | ALPHA-Thrombin heavy chain | polymer | 259 | 29780.2 | 1 | UniProt (P00734) Pfam (PF00089) | Homo sapiens (human) | COAGULATION FACTOR II, THROMBIN |
4 | D (H) | D-phenylalanyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-prolinamide | non-polymer | 451.0 | 1 | BIRD (PRD_000021) Chemie (0G7) | |||
5 | E, F, G (D, L, H) | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 38619.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 451.0 | |
All* | Total formula weight | 39070.8 |