1HQ2

CRYSTAL STRUCTURE OF A TERNARY COMPLEX OF E.COLI HPPK(R82A) WITH MGAMPCPP AND 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN AT 1.25 ANGSTROM RESOLUTION

1HQ2 の概要

• エントリーDOI: 10.2210/pdb1hq2/pdb
• 関連するPDBエントリー: 1CBK 1DY3 1EQ0 1EQM 1EQO 1EX8 1F9H 1F9Y 1G4C 1HKA
• 分子名称: 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, MAGNESIUM ION, CHLORIDE ION, ... (7 entities in total)
• 機能のキーワード: pyrophosphokinase, pyrophosphoryl transfer, catalytic mechanism, folate, hppk, pterin, 6-hydroxymethyl-7, 8-dihydropterin, ternary complex, substrate specificity, antimicrobial agent, drug design, transferase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18901.04

構造登録者

Blaszczyk, J.,Ji, X. (登録日: 2000-12-13, 公開日: 2003-04-15, 最終更新日: 2023-08-30)

• 主引用文献: Blaszczyk, J.,Li, Y.,Shi, G.,Yan, H.,Ji, X.; Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies; Biochemistry, 42:1573-1580, 2003; PubMed: 12578370; DOI: 10.1021/bi0267994

実験手法

X-RAY DIFFRACTION (1.25 Å)