1HCQ

THE CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO DNA: HOW RECEPTORS DISCRIMINATE BETWEEN THEIR RESPONSE ELEMENTS

1HCQ の概要

• エントリーDOI: 10.2210/pdb1hcq/pdb
• 分子名称: DNA (5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*CP*AP*GP*TP*GP*AP*CP*CP*T P*G)-3'), DNA (5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*CP*TP*GP*TP*GP*AP*CP*CP*T P*G)-3'), PROTEIN (ESTROGEN RECEPTOR), ... (5 entities in total)
• 機能のキーワード: protein-dna complex, complexed with drug, transcription-dna complex, transcription/dna
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Isoform 1: Nucleus. Isoform 3: Nucleus: P03372
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 61356.59

構造登録者

Schwabe, J.W.R.,Chapman, L.,Finch, J.T.,Rhodes, D. (登録日: 1995-01-04, 公開日: 1995-11-23, 最終更新日: 2022-12-21)

• 主引用文献: Schwabe, J.W.,Chapman, L.,Finch, J.T.,Rhodes, D.; The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements.; Cell(Cambridge,Mass.), 75:567-578, 1993; PubMed: 8221895; DOI: 10.1016/0092-8674(93)90390-C

実験手法

X-RAY DIFFRACTION (2.4 Å)