1HCF

Crystal structure of TrkB-d5 bound to neurotrophin-4/5

Summary for 1HCF

• Entry DOI: 10.2210/pdb1hcf/pdb
• Related: 1B8M 1B98 1WWB
• Descriptor: NEUROTROPHIN-4, BDNF/NT-3 GROWTH FACTORS RECEPTOR, SULFATE ION, ... (4 entities in total)
• Functional Keywords: transferase/hormone, complex(transferase-growth factor), neurotrophin-4/5, trkb receptor, ngf-beta superfamily, immunoglobulin domain, transferase-hormone complex
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Secreted: P34130; Membrane; Single-pass type I membrane protein: Q16620
• Total number of polymer chains: 4
• Total formula weight: 51365.50

Authors

Banfield, M.J.,Naylor, R.L.,Robertson, A.G.S.,Allen, S.J.,Dawbarn, D.,Brady, R.L. (deposition date: 2001-05-03, release date: 2001-12-06, Last modification date: 2023-12-13)

• Primary citation: Banfield, M.J.,Naylor, R.L.,Robertson, A.G.S.,Allen, S.J.,Dawbarn, D.,Brady, R.L.; Specificity in Trk-Receptor:Neurotrophin Interaction: The Crystal Structure of Trkb-D5 in Complex with Neurotrophin-4/5; Structure, 9:1191-, 2001; PubMed: 11738045; DOI: 10.1016/S0969-2126(01)00681-5

Experimental method

X-RAY DIFFRACTION (2.7 Å)