Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1H9U

The structure of the human retinoid-X-receptor beta ligand binding domain in complex with the specific synthetic agonist LG100268

Summary for 1H9U
Entry DOI10.2210/pdb1h9u/pdb
DescriptorRETINOID X RECEPTOR, BETA, 6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)CYCLOPROPYL]PYRIDINE-3-CARBOXYLIC ACID, NICKEL (II) ION, ... (5 entities in total)
Functional Keywordsnuclear receptor, rxr, transcription factor
Biological sourceHOMO SAPIENS
Cellular locationNucleus: P28702
Total number of polymer chains4
Total formula weight101130.23
Authors
Schwabe, J.W.R.,Love, J.D.,Gooch, J.T. (deposition date: 2001-03-21, release date: 2002-04-03, Last modification date: 2023-12-13)
Primary citationLove, J.D.,Gooch, J.T.,Benko, S.,Li, C.,Nagy, L.,Chatterjee, V.K.K.,Evans, R.M.,Schwabe, J.W.R.
The Structural Basis for the Specificity of Retinoid-X Receptor-Selective Agonists: New Insights Into the Role of Helix H12
J.Biol.Chem., 277:11385-, 2002
Cited by
PubMed: 11782480
DOI: 10.1074/JBC.M110869200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.7 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon