1H9U
The structure of the human retinoid-X-receptor beta ligand binding domain in complex with the specific synthetic agonist LG100268
Summary for 1H9U
Entry DOI | 10.2210/pdb1h9u/pdb |
Descriptor | RETINOID X RECEPTOR, BETA, 6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)CYCLOPROPYL]PYRIDINE-3-CARBOXYLIC ACID, NICKEL (II) ION, ... (5 entities in total) |
Functional Keywords | nuclear receptor, rxr, transcription factor |
Biological source | HOMO SAPIENS |
Cellular location | Nucleus: P28702 |
Total number of polymer chains | 4 |
Total formula weight | 101130.23 |
Authors | Schwabe, J.W.R.,Love, J.D.,Gooch, J.T. (deposition date: 2001-03-21, release date: 2002-04-03, Last modification date: 2023-12-13) |
Primary citation | Love, J.D.,Gooch, J.T.,Benko, S.,Li, C.,Nagy, L.,Chatterjee, V.K.K.,Evans, R.M.,Schwabe, J.W.R. The Structural Basis for the Specificity of Retinoid-X Receptor-Selective Agonists: New Insights Into the Role of Helix H12 J.Biol.Chem., 277:11385-, 2002 Cited by PubMed: 11782480DOI: 10.1074/JBC.M110869200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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