The structure of CMP:2-keto-3-deoxy-manno-octonic acid synthetase and of its complexes with substrates and substrate analogues, here complex with CMP-NeuAc

Summary for 1H7T

Related1H6J 1H7E 1H7F 1H7G 1H7H
Descriptor3-DEOXY-MANNO-OCTULOSONATE CYTIDYLYLTRANSFERASE, CYTIDINE-5'-MONOPHOSPHATE, N-acetyl-alpha-neuraminic acid, ... (4 entities in total)
Functional Keywordsnucleotidyltransferase, cmp-kdo synthetase, nucleoside monophosphate glycosides, lipopolysaccharide biosynthesis, sugar-activating enzymes, transferase
Biological sourceESCHERICHIA COLI
Total number of polymer chains2
Total molecular weight54752.29
Jelakovic, S.,Schulz, G.E. (deposition date: 2001-07-10, release date: 2001-09-13, Last modification date: 2020-07-29)
Primary citation
Jelakovic, S.,Schulz, G.E.
The Structure of Cmp:2-Keto-3-Deoxy-Manno-Octonic Acid Synthetase and of its Complexes with Substrates and Substrate Analogs
J.Mol.Biol., 312:143-, 2001
PubMed: 11545592 (PDB entries with the same primary citation)
DOI: 10.1006/JMBI.2001.4948
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2167 0.4% 2.5% 3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-12-02