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1H7T

The structure of CMP:2-keto-3-deoxy-manno-octonic acid synthetase and of its complexes with substrates and substrate analogues, here complex with CMP-NeuAc

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
3-DEOXY-MANNO-OCTULOSONATE CYTIDYLYLTRANSFERASEpolymer24527059.92UniProt (P42216)
Pfam (PF02348)
ESCHERICHIA COLICMP-KDO SYNTHETASE, CKS, CMP-2-KETO-3-DEOXYOCTULOSONIC ACID SYNTHETASE, CMP-2-KETO-3-DEOXY-MANNO -OCTONIC ACID SYNTHETASE
2C
(B)
CYTIDINE-5'-MONOPHOSPHATEnon-polymer323.21Chemie (C5P)
3D
(B)
N-acetyl-alpha-neuraminic acidnon-polymer309.31Chemie (SIA)
4E, F
(A, B)
waterwater18.0206Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight54119.8
Non-Polymers*Number of molecules2
Total formula weight632.5
All*Total formula weight54752.3
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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