1H4W

Structure of human trypsin IV (brain trypsin)

Summary for 1H4W
DescriptorTRYPSIN IVA, BENZAMIDINE, CALCIUM ION, ... (4 entities in total)
Functional Keywordsserine protease, signal transduction, inhibitor resistance, alzheimer disease, hydrolase
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains1
Total formula weight24461.74
Authors
Katona, G.,Berglund, G.I.,Hajdu, J.,Graf, L.,Szilagyi, L. (deposition date: 2001-05-15, release date: 2002-02-11, Last modification date: 2019-02-27)
Primary citationBerglund, G.I.,Graf, L.,Hajdu, J.,Katona, G.,Szilagyi, L.
Crystal structure reveals basis for the inhibitor resistance of human brain trypsin.
J. Mol. Biol., 315:1209-1218, 2002
PubMed: 11827488
DOI: 110.1006/jmbi.2001.5305
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation
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PDB entries from 2021-06-16