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1H15

X-ray crystal structure of HLA-DRA1*0101/DRB5*0101 complexed with a peptide from Epstein Barr Virus DNA polymerase

Summary for 1H15
Entry DOI10.2210/pdb1h15/pdb
Related1A6A 1AQD 1D5M 1D5X 1D5Z 1D6E 1DLH 1FV1 1HQR 1HXY 1J8H 1KG0 1SEB 2SEB
DescriptorHLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR BETA 1 CHAIN, DNA POLYMERASE, ... (6 entities in total)
Functional Keywordsimmune system/transferase, complex (mhc-antigen), immune system, mhc, hla, class ii, dr2, drb5, ebv, dna polymerase, dna-directed dna polymerase, immune system-transferase complex
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationCell membrane; Single-pass type I membrane protein: P01903
Host nucleus: P03198
Total number of polymer chains6
Total formula weight91120.68
Authors
Primary citationLang, H.,Jacobsen, H.,Ikemizu, S.,Andersson, C.,Harlos, K.,Madsen, L.,Hjorth, P.,Sondergaard, L.,Svejgaard, A.,Wucherpfennig, K.,Stuart, D.I.,Bell, J.I.,Jones, E.Y.,Fugger, L.
A Functional and Structural Basis for Tcr Cross-Reactivity in Multiple Sclerosis
Nat.Immunol., 3:940-, 2002
Cited by
PubMed: 12244309
DOI: 10.1038/NI835
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.1 Å)
Structure validation

217157

数据于2024-03-13公开中

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