1GSE

GLUTATHIONE TRANSFERASE A1-1 COMPLEXED WITH AN ETHACRYNIC ACID GLUTATHIONE CONJUGATE (MUTANT R15K)

Summary for 1GSE

DescriptorGLUTATHIONE TRANSFERASE, GLUTATHIONE, ETHACRYNIC ACID, ... (5 entities in total)
Functional Keywordsa1-1, transferase (glutathione)
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm P08263
Total number of polymer chains2
Total molecular weight52555.27
Authors
Cameron, A.D.,Jones, T.A. (deposition date: 1995-06-09, release date: 1995-09-15, Last modification date: 2011-11-16)
Primary citation
Cameron, A.D.,Sinning, I.,L'Hermite, G.,Olin, B.,Board, P.G.,Mannervik, B.,Jones, T.A.
Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate.
Structure, 3:717-727, 1995
PubMed: 8591048 (PDB entries with the same primary citation)
DOI: 10.1016/S0969-2126(01)00206-4
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers90.5%2.8%5.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1gse
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Molmil generated image of 1gse
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Molmil generated image of 1gse
rotated about y axis by 90°