1GPU
Transketolase complex with reaction intermediate
Summary for 1GPU
Entry DOI | 10.2210/pdb1gpu/pdb |
Related | 1AY0 1NGS 1TKA 1TKB 1TKC 1TRK |
Descriptor | TRANSKETOLASE 1, CALCIUM ION, 2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | transferase(ketone residues), transferase |
Biological source | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) |
Total number of polymer chains | 2 |
Total formula weight | 148823.65 |
Authors | Fiedler, E.,Thorell, S.,Sandalova, T.,Koenig, S.,Schneider, G. (deposition date: 2001-11-09, release date: 2002-02-11, Last modification date: 2023-12-13) |
Primary citation | Fiedler, E.,Thorell, S.,Sandalova, T.,Golbik, R.,Koenig, S.,Schneider, G. Snapshot of a Key Intermediate in Enzymatic Thiamin Catalysis: Crystal Structure of the Alpha-Carbanion of (Alpha,Beta-Dihydroxyethyl)-Thiamin Diphosphate in the Active Site of Transketolase from Saccharomyces Cerevisiae. Proc.Natl.Acad.Sci.USA, 99:591-, 2002 Cited by PubMed: 11773632DOI: 10.1073/PNAS.022510999 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.86 Å) |
Structure validation
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