1GKD

MMP9 active site mutant-inhibitor complex

Summary for 1GKD

Descriptor92 KDA TYPE IV COLLAGENASE, CALCIUM ION, 2-{[FORMYL(HYDROXY)AMINO]METHYL}-4-METHYLPENTANOIC ACID, ... (6 entities in total)
Functional Keywordsmatrix metalloprotease, hydrolase, glycoprotein
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationSecreted, extracellular space, extracellular matrix (Probable) P14780
Total number of polymer chains2
Total molecular weight38015.96
Authors
Rowsell, S.,Pauptit, R.A. (deposition date: 2001-08-10, release date: 2002-05-16, Last modification date: 2011-07-13)
Primary citation
Rowsell, S.,Hawtin, P.,Minshull, C.A.,Jepson, H.,Brockbank, S.,Barratt, D.,Slater, A.M.,Mcpheat, W.,Waterson, D.,Henney, A.,Pauptit, R.A.
Crystal Structure of Mmp9 in Complex with a Reverse Hydroxamate Inhibitor
J.Mol.Biol., 319:173-, 2002
PubMed: 12051944 (PDB entries with the same primary citation)
DOI: 10.1016/S0022-2836(02)00262-0
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.1 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.250701.6%4.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution