1GKD
MMP9 active site mutant-inhibitor complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | 92 KDA TYPE IV COLLAGENASE | polymer | 163 | 18383.4 | 2 | UniProt (P14780) Pfam (PF00413) In PDB | HOMO SAPIENS (HUMAN) | MMP-9,92 KDA GELATINASE, GELATINASE B, MATRIX METALLOPROTEINASE-9 |
2 | A, B | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
3 | A, B | 2-{[FORMYL(HYDROXY)AMINO]METHYL}-4-METHYLPENTANOIC ACID | non-polymer | 189.2 | 2 | Chemie (STN) | |||
4 | A, B | 2-AMINO-N,3,3-TRIMETHYLBUTANAMIDE | non-polymer | 144.2 | 2 | Chemie (BUM) | |||
5 | A, B | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
6 | water | water | 18.0 | 184 | Chemie (HOH) |
Sequence modifications
A, B: 106 - 106 (PDB: 1GKD)
A, B: 107 - 215 (UniProt: P14780)
A, B: 391 - 443 (UniProt: P14780)
A, B: 107 - 215 (UniProt: P14780)
A, B: 391 - 443 (UniProt: P14780)
PDB | External Database | Details |
---|---|---|
Gln 402 | Glu 402 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 36766.8 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 1249.1 | |
All* | Total formula weight | 38016.0 |