1G32

THROMBIN INHIBITOR COMPLEX

Summary for 1G32
DescriptorPROTHROMBIN, HIRUDIN IIB, 4-{[1-METHYL-5-(2-METHYL-BENZOIMIDAZOL-1-YLMETHYL)-1H-BENZOIMIDAZOL-2-YLMETHYL]-AMINO}-BENZAMIDINE, ... (5 entities in total)
Functional Keywordsblood coagulation; factor xa; inhibitor complexes, serine proteinase, blood coagulation cascade, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted, extracellular space: P00734 P00734
Secreted: P28506
Total number of polymer chains3
Total formula weight35791.79
Authors
Nar, H. (deposition date: 2000-10-23, release date: 2001-10-23, Last modification date: 2013-03-13)
Primary citationBauer, M.,Hauel, N.H.,Kauffmann, I.K.,Nar, H.,Priepke, H.W.,Ries, U.J.,Schmid, A.,Stassen, J.M.,Wienen, W.
Structural basis for inhibition promiscuity of dual specific thrombin and factor Xa blood coagulation inhibitors.
Structure, 9:29-38, 2001
PubMed: 11342132
DOI: 110.1016/S0969-2126(00)00551-7
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.9 Å)
Structure validation
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178938

PDB entries from 2021-06-16